Research Programs

Cardiovascular Genomics: Cardiovascular genomics is a cutting edge translational research area at Duke. Studies range from basic mechanistic approaches to identification of high-risk groups and genomic predictors, to incorporation of genomic tools into daily clinical decision-making.
Cancer Genomics: What do we know about cancer that might enable us to fight it? We know that it is characterized by genomic instability-tumor cells divide like mad and in that process their genomes are rarely transmitted faithfully. Breast cancer is no exception: any ten women with the disease will have ten different tumors-their cancers will be of different sizes, some will be more aggressive than others, and those tumors will each express their own peculiar set of genes (albeit with some overlap).
Genome Biology: The essentially complete decoding of the entire human genome sequence in 2003 was a landmark event. However, one could argue that sequencing was the easy part. Now is when the really hard work begins: what do these three billion base pairs mean? We know that the overwhelming majority do not code for proteins.

IGSP Centers