Joseph R. Nevins, PhD
Publications
Giangrande PH, Zhang J, Tanner A, Eckhart AD, Rempel RE, Andrechek ER, Layzer JM, Keys JR, Hagen PO, Nevins JR, Koch WJ, Sullenger BA.
Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia.
Proc Natl Acad Sci U S A. 2007 Jul 25; [Epub ahead of print]
PMID: 17652516 [PubMed - as supplied by publisher]
Nevins JR, Potti A.
Mining gene expression profiles: expression signatures as cancer phenotypes.
Nat Rev Genet. 2007 Aug;8(8):601-9. Epub 2007 Jul 3.
PMID: 17607306 [PubMed - in process]
Dressman HK, Muramoto GG, Chao NJ, Meadows S, Marshall D, Ginsburg GS, Nevins JR, Chute JP.
Gene expression signatures that predict radiation exposure in mice and humans.
PLoS Med. 2007 Apr;4(4):e106.
PMID: 17407386 [PubMed - indexed for MEDLINE]
Dressman HK, Berchuck A, Chan G, Zhai J, Bild A, Sayer R, Cragun J, Clarke J, Whitaker RS, Li L, Gray J, Marks J, Ginsburg GS, Potti A, West M, Nevins JR, Lancaster JM.
An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer.
J Clin Oncol. 2007 Feb 10;25(5):517-25.
PMID: 17290060 [PubMed - indexed for MEDLINE]
Potti A, Dressman HK, Bild A, Riedel RF, Chan G, Sayer R, Cragun J, Cottrill H, Kelley MJ, Petersen R, Harpole D, Marks J, Berchuck A, Ginsburg GS, Febbo P, Lancaster J, Nevins JR.
Genomic signatures to guide the use of chemotherapeutics.
Nat Med. 2006 Nov;12(11):1294-300. Epub 2006 Oct 22.
PMID: 17057710 [PubMed - indexed for MEDLINE]
Lancaster JM, Dressman HK, Clarke JP, Sayer RA, Martino MA, Cragun JM, Henriott AH, Gray J, Sutphen R, Elahi A, Whitaker RS, West M, Marks JR, Nevins JR, Berchuck A.
Identification of genes associated with ovarian cancer metastasis using microarray expression analysis.
Int J Gynecol Cancer. 2006 Sep-Oct;16(5):1733-45.
PMID: 17009964 [PubMed - indexed for MEDLINE]
Cheng SH, Horng CF, West M, Huang E, Pittman J, Tsou MH, Dressman H, Chen CM, Tsai SY, Jian JJ, Liu MC, Nevins JR, Huang AT.
Genomic prediction of locoregional recurrence after mastectomy in breast cancer.
J Clin Oncol. 2006 Oct 1;24(28):4594-602.
PMID: 17008701 [PubMed - indexed for MEDLINE]
Chang JT, Nevins JR.
GATHER: a systems approach to interpreting genomic signatures.
Bioinformatics. 2006 Dec 1;22(23):2926-33. Epub 2006 Sep 25.
PMID: 17000751 [PubMed - indexed for MEDLINE]
Bild AH, Potti A, Nevins JR.
Linking oncogenic pathways with therapeutic opportunities.
Nat Rev Cancer. 2006 Sep;6(9):735-41. Epub 2006 Aug 17. Review.
PMID: 16915294 [PubMed - indexed for MEDLINE]
Kong LJ, Chang JT, Bild AH, Nevins JR.
Compensation and specificity of function within the E2F family.
Oncogene. 2007 Jan 18;26(3):321-7. Epub 2006 Aug 14.
PMID: 16909124 [PubMed - indexed for MEDLINE]
Potti A, Mukherjee S, Petersen R, Dressman HK, Bild A, Koontz J, Kratzke R, Watson MA, Kelley M, Ginsburg GS, West M, Harpole DH Jr, Nevins JR.
A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer.
N Engl J Med. 2006 Aug 10;355(6):570-80. Erratum in: N Engl J Med. 2007 Jan 11;356(2):201-2.
PMID: 16899777 [PubMed - indexed for MEDLINE]
West M, Ginsburg GS, Huang AT, Nevins JR.
Embracing the complexity of genomic data for personalized medicine.
Genome Res. 2006 May;16(5):559-66. Review.
PMID: 16651662 [PubMed - indexed for MEDLINE]
Kong LJ, Meloni AR, Nevins JR.
The Rb-related p130 protein controls telomere lengthening through an interaction with a Rad50-interacting protein, RINT-1.
Mol Cell. 2006 Apr 7;22(1):63-71.
PMID: 16600870 [PubMed - indexed for MEDLINE]
Hallstrom TC, Nevins JR.
Jab1 is a specificity factor for E2F1-induced apoptosis.
Genes Dev. 2006 Mar 1;20(5):613-23. Epub 2006 Feb 15.
PMID: 16481464 [PubMed - indexed for MEDLINE]
Dressman HK, Hans C, Bild A, Olson JA, Rosen E, Marcom PK, Liotcheva VB, Jones EL, Vujaskovic Z, Marks J, Dewhirst MW, West M, Nevins JR, Blackwell K.
Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy.
Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):819-26.
PMID: 16467094 [PubMed - indexed for MEDLINE]
Karra R, Vemullapalli S, Dong C, Herderick EE, Song X, Slosek K, Nevins JR, West M, Goldschmidt-Clermont PJ, Seo D.
Molecular evidence for arterial repair in atherosclerosis.
Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16789-94. Epub 2005 Nov 7.
PMID: 16275914 [PubMed - indexed for MEDLINE]
Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, Joshi MB, Harpole D, Lancaster JM, Berchuck A, Olson JA Jr, Marks JR, Dressman HK, West M, Nevins JR.
Oncogenic pathway signatures in human cancers as a guide to targeted therapies.
Nature. 2006 Jan 19;439(7074):353-7. Epub 2005 Nov 6.
PMID: 16273092 [PubMed - indexed for MEDLINE]
Potti A, Bild A, Dressman HK, Lewis DA, Nevins JR, Ortel TL.
Gene-expression patterns predict phenotypes of immune-mediated thrombosis.
Blood. 2006 Feb 15;107(4):1391-6. Epub 2005 Nov 1.
PMID: 16263789 [PubMed - indexed for MEDLINE]
Meloni AR, Lai CH, Yao TP, Nevins JR.
A mechanism of COOH-terminal binding protein-mediated repression.
Mol Cancer Res. 2005 Oct;3(10):575-83.
PMID: 16254191 [PubMed - indexed for MEDLINE]
Black EP, Hallstrom T, Dressman HK, West M, Nevins JR.
Distinctions in the specificity of E2F function revealed by gene expression signatures.
Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15948-53. Epub 2005 Oct 25.
PMID: 16249342 [PubMed - indexed for MEDLINE]
Rich JN, Hans C, Jones B, Iversen ES, McLendon RE, Rasheed BK, Dobra A, Dressman HK, Bigner DD, Nevins JR, West M.
Gene expression profiling and genetic markers in glioblastoma survival.
Cancer Res. 2005 May 15;65(10):4051-8.
PMID: 15899794 [PubMed - indexed for MEDLINE]
Berchuck A, Iversen ES, Lancaster JM, Pittman J, Luo J, Lee P, Murphy S, Dressman HK, Febbo PG, West M, Nevins JR, Marks JR.
Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers.
Clin Cancer Res. 2005 May 15;11(10):3686-96.
PMID: 15897565 [PubMed - indexed for MEDLINE]
Zhu W, Giangrande PH, Nevins JR.
Temporal control of cell cycle gene expression mediated by E2F transcription factors.
Cell Cycle. 2005 May;4(5):633-6. Epub 2005 May 2.
PMID: 15876877 [PubMed - indexed for MEDLINE]
Delong M, Yao G, Wang Q, Dobra A, Black EP, Chang JT, Bild A, West M, Nevins JR, Dressman H.
DIG--a system for gene annotation and functional discovery.
Bioinformatics. 2005 Jul 1;21(13):2957-9. Epub 2005 May 3.
PMID: 15870167 [PubMed - indexed for MEDLINE]
Giangrande PH, Zhu W, Schlisio S, Sun X, Mori S, Gaubatz S, Nevins JR.
A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription.
Genes Dev. 2004 Dec 1;18(23):2941-51.
PMID: 15574595 [PubMed - indexed for MEDLINE]
Zhu W, Giangrande PH, Nevins JR.
E2Fs link the control of G1/S and G2/M transcription.
EMBO J. 2004 Nov 24;23(23):4615-26. Epub 2004 Oct 28.
PMID: 15510213 [PubMed - indexed for MEDLINE]
Huang ES, Nevins JR, West M, Kuo PC.
An overview of genomic data analysis.
Surgery. 2004 Sep;136(3):497-9. No abstract available.
PMID: 15349091 [PubMed - indexed for MEDLINE]
Seo D, Wang T, Dressman H, Herderick EE, Iversen ES, Dong C, Vata K, Milano CA, Rigat F, Pittman J, Nevins JR, West M, Goldschmidt-Clermont PJ.
Gene expression phenotypes of atherosclerosis.
Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1922-7. Epub 2004 Aug 5.
PMID: 15297278 [PubMed - indexed for MEDLINE]
Wells SA, Nevins JR.
Evolving strategies for targeted cancer therapy--past, present, and future.
J Natl Cancer Inst. 2004 Jul 7;96(13):980-1. No abstract available.
PMID: 15240773 [PubMed - indexed for MEDLINE]
Pittman J, Huang E, Dressman H, Horng CF, Cheng SH, Tsou MH, Chen CM, Bild A, Iversen ES, Huang AT, Nevins JR, West M.
Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes.
Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8431-6. Epub 2004 May 19.
PMID: 15152076 [PubMed - indexed for MEDLINE]
Berchuck A, Iversen ES, Lancaster JM, Dressman HK, West M, Nevins JR, Marks JR.
Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays.
Am J Obstet Gynecol. 2004 Apr;190(4):910-25.
PMID: 15118612 [PubMed - indexed for MEDLINE]
Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G, Hahn WC, Stukenberg PT, Shenolikar S, Uchida T, Counter CM, Nevins JR, Means AR, Sears R.
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
Nat Cell Biol. 2004 Apr;6(4):308-18. Epub 2004 Mar 14.
PMID: 15048125 [PubMed - indexed for MEDLINE]
Giangrande PH, Zhu W, Rempel RE, Laakso N, Nevins JR.
Combinatorial gene control involving E2F and E Box family members.
EMBO J. 2004 Mar 24;23(6):1336-47. Epub 2004 Mar 4.
PMID: 15014447 [PubMed - indexed for MEDLINE]
Lancaster JM, Dressman HK, Whitaker RS, Havrilesky L, Gray J, Marks JR, Nevins JR, Berchuck A.
Gene expression patterns that characterize advanced stage serous ovarian cancers.
J Soc Gynecol Investig. 2004 Jan;11(1):51-9.
PMID: 14706684 [PubMed - indexed for MEDLINE]
Cook JG, Chasse DA, Nevins JR.
The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells.
J Biol Chem. 2004 Mar 5;279(10):9625-33. Epub 2003 Dec 11.
PMID: 14672932 [PubMed - indexed for MEDLINE]
Huang ES, Black EP, Dressman H, West M, Nevins JR.
Gene expression phenotypes of oncogenic signaling pathways.
Cell Cycle. 2003 Sep-Oct;2(5):415-7. Review. No abstract available.
PMID: 12963829 [PubMed - indexed for MEDLINE]
Hallstrom TC, Nevins JR.
Specificity in the activation and control of transcription factor E2F-dependent apoptosis.
Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10848-53. Epub 2003 Sep 3.
PMID: 12954980 [PubMed - indexed for MEDLINE]
Nevins JR, Huang ES, Dressman H, Pittman J, Huang AT, West M.
Towards integrated clinico-genomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction.
Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R153-7. Epub 2003 Aug 19. Review.
PMID: 12928487 [PubMed - indexed for MEDLINE]
Black EP, Huang E, Dressman H, Rempel R, Laakso N, Asa SL, Ishida S, West M, Nevins JR.
Distinct gene expression phenotypes of cells lacking Rb and Rb family members.
Cancer Res. 2003 Jul 1;63(13):3716-23.
PMID: 12839964 [PubMed - indexed for MEDLINE]
Huang E, West M, Nevins JR.
Gene expression profiling for prediction of clinical characteristics of breast cancer.
Recent Prog Horm Res. 2003;58:55-73. Review.
PMID: 12795414 [PubMed - indexed for MEDLINE]
Contact Information
Joseph R. Nevins
Phone: 919-684-2746
2121 CIEMAS
j.nevins@duke.edu
Kaye Culler
Administrative Coordinator
Phone: 919-684-2746
2121 CIEMAS
kaye.culler@duke.edu